The 34-year-old made two World Cup final appearances and earned 75 caps for the Red Roses.
After giving birth to twins last summer, she has been on maternity leave from the English system.
Having twins is incredibly difficult, so even though I’m probably the strongest I’ve ever been, mentally I’m not there yet, Cornborough told news Sport.
A high-performance pressure setting is not one where one can function well on a few hours of sleep per night.
It is natural for me to step away from the Red Roses and declare my retirement.