The 22-year-old was selected among a record six quarterbacks in the first 12 picks; he has long been considered one of the best players to emerge from college.
For the first time in NFL Draft history, no defensive player was selected in the top 10, as the evening began with 14 straight offensive players selected.
The first round of the draft attracted a record 250,000 spectators to downtown Detroit. Six more rounds of selection are scheduled on Friday and Saturday.
Jayden Daniels came after the first three quarterbacks off the board for only the fourth time.