Slade has not yet played for Exeter this season due to shoulder surgery following the summer trip to New Zealand, while Curry of Sale returned from a concussion layoff in Friday’s victory against Newcastle.
Ben Spencer, Jack van Poortvliet, and Harry Randall are the three designated scrum-halves in Mitchell’s absence.
The other specialist standoffs are Marcus Smith and Fin Smith, while George Ford of Sale will continue his recovery from a torn quad muscle.
In other places Alex Lozowski of the Saracens takes Fraser Dingwall’s position as the injured Harlequins center, and Luke Northmore searches for his team.
rear row Despite an outstanding start to the season, Tom Willis is left off the roster; however, Ben, the twin brother of Tom Curry, and Alex Dombrandt, the number eight for the Harlequins, who is recovering from a broken hand, are included.