Researchers gave anti-IL-11 antibody injections to 75-week-old mice in an attempt to lessen the negative effects of IL-11.
Researchers at the Medical Research Council Laboratory of Medical Sciences and Imperial College London have suppressed IL-11, a protein that can help mice live longer, healthy lives by more than 25%.
It offers reassuring insights and may have a similar effect on others.
The Duke NUS Medical School in Singapore collaborated with the scientists. The researchers were able to investigate the effects of interleukin 11 (IL-11) by genetically altering mice lacking the IL-11 gene.
During the course of their research, the scientists also gave 75-week-old mice an injection of an anti-IL-11 antibody, a drug that mitigates the harmful effects of IL-11.Published in the journal Nature, the new findings “suggest that those potential treatments might also have an impact on longevity, but separate clinical trials are needed to be certain,” the study’s paper notes.
Nevertheless, IL-11 is distinct from a plethora of other proteins and rejuvenation treatments that have shown potential in animal models but have faced challenges during their journey to human clinical trials.
