According to a statement from his family, Prince Frederik of Luxembourg died on March 1, 2025, at the age of 22.
Prince Robert of Luxembourg and Princess Julie of Nassau had a younger son.
POLG mitochondrial disease, a rare genetic ailment he had fought since being identified at the age of 14, was the cause of his death.
His family made the announcement, with his father posting a moving remembrance on the POLG Foundation website—a group Frederik established to fund disease research.
