The 26-year-old left-back missed Sunday’s victory at Ross County due to a calf injury he sustained during Borussia Dortmund’s midweek Champions League loss.
The 14-time captained Taylor did not play in the team throughout this campaign’s opening defeats to Portugal and Poland.
Due to injuries, head coach Steve Clarke has already lost ten players, and Angus Gunn’s status is uncertain.
After receiving a hard blow to the ribs at the halftime break against Hull City on Saturday, the goalie for Norwich City was taken off the field.
Among those not available is vice captain John McGinn; new call-ups Andy Irving, Liam Lindsay, and Nicky Devlin.
Scotland will play host to Portugal three days after visiting Zagreb on Saturday.
Scotland has zero points, Poland and Croatia have three, and Portugal is first in Group A1 with six points.
