Booker scored 33 points and Durant scored 30 to help the Suns win 109-105 at the Footprint Center in Phoenix.
Austin Reaves scored 23 points and teammate Anthony Davis scored 29 points, while Lakers star LeBron James had a quiet game and only scored 11.
With a 3-0 record to begin the season under new head coach JJ Redick, the Lakers entered the game and got off to an outstanding start.
The Lakers led 26-8 after Davis scored 16 points in the first quarter.
