On the last hill of the day, American Faulkner attacked from five kilometers out and managed to win by himself, 10 seconds ahead of a group of seventeen riders.
Georgia Baker of Australia came in second, outpacing Vos in third, who leads the general classification standings by five seconds.
The 31-year-old Faulkner won two stages at the Giro d’Italia Donne in 2022, but this was her maiden Vuelta victory.
After Alison Jackson ran to victory on Monday, her Education-Cannondale team won their second stage of the tour this year.
I anticipated that many teams would attempt to attack that climb. Demi Vollering and Elisa Longo Borghini launched an attack, and I was right in their wheelhouse,” said Faulkner.