One of the four primary pre-race favorites, the 34-year-old Slovenian finished Thursday’s 204-kilometer stage from Aurillac to Villeneuve-sur-Lot with a bloodied right shoulder after an incident that occurred 10 kilometers from the finish.
After losing two minutes and 27 seconds to the leaders in the general classification, Roglic fell from fourth to sixth in the accident.
Red Bull-Bora-Hansgrohe said in a statement that Roglic will now be concentrating on “upcoming goals”.
The team continued, saying: “After yesterday’s stage and again this morning, Primoz Roglic was thoroughly examined by our medical experts.
It has been decided that he will not begin on Friday.
Stage 13 takes riders 165.3 kilometers from Agen to Pau on Friday.
On Wednesday, during the last descent of Stage 11, Roglic also got into a late crash after his back tire skidded out of a narrow left-hand turn.