Off-label use of rapamycin, also known as sirolimus, an immune-suppressive drug, is being used to increase longevity.
“This medication has been demonstrated to increase lifespan in animals by targeting a key pathway (mTOR) in cells, and it may help prevent age-related diseases in humans,” Dr. Andrea B. Maier, a professor of healthy aging and dementia research at the National University of Singapore’s Center for Healthy Longevity, told News.
Review results showed that the drug lessened the negative effects of aging on the skin. The review was published in the journal Lancet Healthy Longevity.
In a message, Maier stated, “Rapamycin and its derivatives enhance the immunological and cardiovascular function of healthy individuals or individuals with aging-related diseases.”
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Molecular researcher Daniel Tawfik says his team utilizes rapamycin to help slow down the process of aging. Tawfik is co-founder of Healthspan, a digital medical clinic that specializes on anti-aging and longevity-promoting medicines.
“We see this as a way to lessen the build-up of damaged senescent cells,” Santa Monica, California-based Tawfik told News.
