The Thermo Scientific™ Orbitrap Exploris™ EFOX Mass Detector delivers a groundbreaking solution for environmental and food safety laboratories. It combines high-resolution analysis with streamlined workflows, enabling faster and more confident PFAS detection without the complexity or high cost of traditional systems.
Environmental and food labs face an expanding range of contaminants, from new PFAS compounds to pesticide degradants and industrial chemicals. Each sample carries the weight of public health responsibility. Analysts need tools that are both precise and practical for routine operations.
The Orbitrap Exploris EFOX Mass Detector empowers labs to meet these demands, providing research-grade performance built for everyday use.
Challenges with Conventional LCMS Workflows
High-resolution accurate mass (HRAM) systems offer exceptional capabilities but often create barriers for routine labs:
- Methods require compound-specific MS/MS optimization
- Adding new compounds demands time-consuming revalidation
- Data review requires specialized expertise
- Method development slows throughput
- Costs limit adoption in smaller labs
- Evolving regulations require future-proof solutions
As regulatory requirements, particularly for PFAS, continue to increase, labs need systems that reduce complexity and accelerate compliance.
Orbitrap Exploris EFOX: Designed for Routine Labs
The Orbitrap Exploris EFOX Mass Detector addresses these challenges. It offers:
- Full-scan HRAM acquisition, eliminating the need for MS/MS optimization
- Retrospective analysis for future-proof workflows
- Compliance-ready methods for PFAS, pesticides, and emerging contaminants
- Accessible pricing for routine laboratories
- Intuitive workflows via Thermo Scientific™ Chromeleon™ software
- Seamless integration with Thermo Scientific™ Vanquish™ UHPLC systems
Aristide Ganci, product manager, explains: “We designed the EFOX to remove complexity, accelerate compliance, and give labs confidence to protect public health.”
Simplified, High-Resolution Workflows
The system captures every ion in every run, giving laboratories unprecedented flexibility. Users can:
- Add new analytes without redeveloping methods
- Screen for emerging contaminants instantly
- Perform quantitation and suspect screening simultaneously
Smart CID fragmentation produces richer spectra, improving ion-ratio confirmation, compound identification, and library searching while eliminating interference.
Retrospective analysis allows labs to revisit data to comply with future regulations, providing answers before questions arise.
A Complete, Reliable Ecosystem
The Orbitrap Exploris EFOX Mass Detector integrates seamlessly with:
- Vanquish™ Flex dual-channel UHPLC
- Dual Split Sampler
- OptaMax™ NG and EASY-IC™ ion sources
- Chromeleon software with guided control and reporting
This ecosystem ensures a modern, durable workflow that can withstand the demands of heavy routine use.
Accelerating PFAS Compliance and Emerging Contaminant Testing
With application-ready workflows, the system simplifies PFAS detection, quantitation, and broad-spectrum pesticide screening. Labs can also handle profiling, identification, and suspect analysis of new organic xenobiotics, keeping them ahead of regulatory changes.
Empowering Labs for a Safer Future
The Orbitrap Exploris EFOX Mass Detector reduces complexity, increases throughput, and improves decision-making. Labs can deploy new methods quickly, conserve consumables, and reduce technician time, lowering total costs.
High-resolution accuracy and robust data processing enhance confidence in both targeted and untargeted analyses. This clarity supports safer water, cleaner soil, and healthier food. By equipping labs to adapt to evolving contaminants and regulations, the EFOX ensures laboratories remain at the forefront of public and environmental safety.
