According to the interior ministry, the event happened on Thursday in Koutoukale jail, which is situated roughly 50 kilometers (30 miles) northwest of the city, Niamey.
The institution saw two further failed attempts at a jailbreak in 2016 and 2019.
The protection of the junta that took over in the previous year’s coup and attacks by jihadists in the west have put a strain on Niger’s military forces.
How many inmates were able to escape in the most recent jailbreak was not made clear by the ministry in its statement.
Captured Islamist fighters from factions associated with the Islamic State and al-Qaeda in the area are thought to be among them, nevertheless.
Authorities have issued an order for increased surveillance and implemented an overnight curfew over the Tillaberi district. All motor vehicle, bicycle, and pedestrian traffic is restricted during the curfew.
Under military control, Niger and its neighbors, Mali and Burkina Faso, have been fighting to stop the rise in Islamist assaults.
Monday’s attack in the Tillaberi district by alleged al-Qaeda-affiliated jihadist cells claimed the lives of at least 14 soldiers and injured another 11.
Between the villages of Ila Fari and Djangore, the army were ambushed; 24 soldiers are still listed as missing.
The three nations under military leadership have all ejected French soldiers who were fighting Islamist organizations there and have turned to Russia for military support.
