With congenital melanocytic naevus syndrome, or CMN for short, children can have large, painful, or itchy moles covering up to 80% of their body when they are born.
Researchers inhibited a gene called NRAS during trials in mice with CMNS, which caused the mole cells to self-destruct.
In the future, the procedure might be utilized to remove normal moles as well as the enormous moles that are present in CMN patients.
“CMN is physically and mentally challenging for children and adults living with this condition and for their families,” stated Veronica Kinsler, the research leader.
These findings are quite intriguing since they show that genetic treatment not only causes self-destruction.
Although further research is necessary before the medicine may be administered to patients, she issued a warning and expressed hope that human clinical trials will soon start.
Researchers from Great Ormond Street Hospital for Children, UCL Great Ormond Street Institute for Child Health, and the Francis Crick Institute conducted the study.
Its CEO has called the results a breakthrough that might change lives. Caring Matters Now, an organization that supports people with chronic muscle neuropathy, provided some funding for it.
